Chronic Disease Risk Reduction Intake (CDRR)
A DRI category introduced for nutrients where intake reduction is causally linked to lower chronic disease risk independent of effects on classical deficiency, first applied to sodium with a 2,300 mg/day adult value.
Also: CDRR
CDRR represents a shift in DRI methodology: rather than reflecting an avoidance of deficiency or toxicity, it reflects a population intake associated with reduced chronic disease risk based on causal evidence. The 2019 sodium DRI was the first to operationalize this category, setting CDRR at 2,300 mg/day for adults to reduce cardiovascular disease risk.
How one textbook covers it
Modern Nutrition in Health and Disease, 12th ed. — Ch 109: Dietary Reference Intakes
CDRR represents a shift in DRI methodology: rather than reflecting an avoidance of deficiency or toxicity, it reflects a population intake associated with reduced chronic disease risk based on causal evidence. The 2019 sodium DRI was the first to operationalize this category, setting CDRR at 2,300 mg/day for adults to reduce cardiovascular disease risk.
Related terms
DRI, Sodium, UL