Krebs cycle
Aerobic mitochondrial cycle that oxidizes acetyl-CoA to CO2 and generates NADH, FADH2, and GTP/ATP.
Also: Citric acid cycle, TCA cycle, Tricarboxylic acid cycle
Central oxidative pathway in the mitochondrial matrix. Eight enzymatic steps convert citrate back to oxaloacetate while releasing two CO2, producing 3 NADH, 1 FADH2, and 1 GTP/ATP per acetyl-CoA. Provides reducing equivalents for the electron transport chain and intermediates for biosynthesis.
How one textbook covers it
Advanced Nutrition and Human Metabolism, 8th ed. (Gropper) — Glossary
Central oxidative pathway in the mitochondrial matrix. Eight enzymatic steps convert citrate back to oxaloacetate while releasing two CO2, producing 3 NADH, 1 FADH2, and 1 GTP/ATP per acetyl-CoA. Provides reducing equivalents for the electron transport chain and intermediates for biosynthesis.
Related terms
Amphibolic pathway, Anaplerotic reaction, Electron transport chain, Oxidative phosphorylation