Osteoclasts
Cells that break down or resorb bone.
Multinucleated cells of monocyte lineage that resorb bone by acidifying the resorption lacuna and secreting proteolytic enzymes. Regulated by RANK/RANKL/OPG signaling and PTH.
How one textbook covers it
Advanced Nutrition and Human Metabolism, 8th ed. (Gropper) — Glossary
Multinucleated cells of monocyte lineage that resorb bone by acidifying the resorption lacuna and secreting proteolytic enzymes. Regulated by RANK/RANKL/OPG signaling and PTH.
Related terms
Hydroxyapatite, Osteoblasts