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Ubiquitin

Protein that attaches to other proteins to mark them for degradation.

Small protein covalently linked to substrates by E1-E2-E3 enzymes. Polyubiquitination targets proteins for 26S proteasome degradation; mono- and atypical chains regulate signaling, trafficking, and DNA repair.

How one textbook covers it

  • Advanced Nutrition and Human Metabolism, 8th ed. (Gropper)Glossary

    Small protein covalently linked to substrates by E1-E2-E3 enzymes. Polyubiquitination targets proteins for 26S proteasome degradation; mono- and atypical chains regulate signaling, trafficking, and DNA repair.

Related terms

Proteases